Department of Psychological Sciences, Purdue University

Purdue Institute for Integrative Neuroscience

making memories since 2014

Sangha Lab 

Science can be hard. It's important to have fun.

Susan Sangha, PhD

Assistant Professor of Neuroscience

Department of Psychological Sciences

Purdue Institute for Integrative Neuroscience

What we do


Clinical disorders arising from maladaptive emotion regulation present a large burden on society worldwide and many of these disorders show comorbidity, for example, addiction with anxiety disorders. Even though there has been much research on reward and fear processing, the majority of studies have been conducted in parallel, investigating the neuronal circuitries separately. Our lab uses a behavioral paradigm designed to assess how safety cues can regulate fear and reward seeking behaviors in rats. We hope by investigating how safety, fear and reward circuits integrate their functions to influence behavior, we will be able to better understand and treat disorders resulting from maladaptive emotion regulation.  

Dr. Susan Sangha receives a 2018 Seed for Success Award for Research in Excellence by Purdue University. See a short video clip about Dr. Sangha's award here

We are recruiting a POSTDOCTORAL FELLOW to join our team focused on the neural circuits of memory. The position is funded by a recently awarded 5-year National Institute of Mental Health R01 grant to investigate the neural circuits of safety, fear and reward cue discrimination. Current studies employ in vivo electrophysiology and pharmacogenetics to monitor and manipulate neural activity during behavior in both male and female rats. We are especially interested in applicants that have a strong background in in vivo electrophysiology and/or techniques for targeting specific neural pathways. However, all applicants enthusiastic about the neurobiology of memory are encouraged to apply. Eligible applicants should have a Ph.D. in neuroscience or a related field. Salary will be commensurate with research experience and based on the NIH guidelines for postdoctoral trainees. Start date flexible, but ideally summer 2019. For additional information, email


Newest publications from the lab:

Müller I, Brinkman AL, Sowinski EM, Sangha S (2018). Adolescent conditioning affects rate of adult fear, safety and reward learning during discriminative conditioning. Scientific Reports 8:17315

Greiner EM, Norris MR, Müller I, Ng KH, Sangha S (2018). Sex differences in fear regulation and reward seeking behaviors in a fear-safety-reward discrimination task.bioRxiv doi:

Sangha S and Foti D (2018). Neurobiology of Abnormal Emotion and Motivated Behaviors: Integrating Animal and Human Research. 1st edition. Cambridge, Massachusetts: Academic Press.

Ng K, Pollock MW, Urbanczyk PJ, Sangha S (2018). Altering D1 receptor activity in the basolateral amygdala impairs fear suppression during a safety cue. Neurobiology of Learning & Memory 147: 26-34