Department of Psychological Sciences, Purdue University

Purdue Institute for Integrative Neuroscience

making memories since 2014

Science can be hard. It's important to have fun.

What we do

 

Clinical disorders arising from maladaptive emotion regulation present a large burden on society worldwide and many of these disorders show comorbidity, for example, addiction with anxiety disorders. Even though there has been much research on reward and fear processing, the majority of studies have been conducted in parallel, investigating the neuronal circuitries separately. Our lab uses a behavioral paradigm designed to assess how safety cues can regulate fear and reward seeking behaviors in rats. We hope by investigating how safety, fear and reward circuits integrate their functions to influence behavior, we will be able to better understand and treat disorders resulting from maladaptive emotion regulation.  

Sangha Lab 

Susan Sangha, PhD

Assistant Professor of Neuroscience

Department of Psychological Sciences

Purdue Institute for Integrative Neuroscience


Sangha Lab receives new funding!
5 year R01 grant from the National Institute of Mental Health titled, "Neural circuitry of safety, fear, and reward cue discrimination"


Newest from the lab:

Greiner EM, Norris MR, Müller I, Ng KH, Sangha S (2018). Sex differences in fear regulation and reward seeking behaviors in a fear-safety-reward discrimination task. bioRxiv doi: https://doi.org/10.1101/390377

Sangha S and Foti D (2018). Neurobiology of Abnormal Emotion and Motivated Behaviors: Integrating Animal and Human Research. 1st edition. Cambridge, Massachusetts: Academic Press.


Ng K, Pollock MW, Urbanczyk PJ, Sangha S (2018). Altering D1 receptor activity in the basolateral amygdala impairs fear suppression during a safety cue. Neurobiology of Learning & Memory 147: 26-34